Péptidos de Suero

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Que es

La fracci—n proteica de la leche contiene diferentes dos grupos principales de prote’nas, las case’nas y las prote’nas del suero l‡cteo. Los pŽptidos son secuencias relativamente peque–as de amino‡cidos y en este caso los pŽptidos de suero son estas peque–as prote’nas que se encuentran en la fracci—n que queda disuelta en el suero despuŽs de la precipitaci—n de las case’nas. Las prote’nas de suero l‡cteo son prote’nas de alta calidad nutricional, resisten la acidez estomacal pasando r‡pidamente al intestino y produciendo un aumento relativamente r‡pido de la concentraci—n de amino‡cidos disponibles en sangre.

Durante la digesti—n o hidr—lisis de las prote’nas tambiŽn se liberan pŽptidos, de hecho la mayor parte de las prote’nas son absorbidas en forma de pŽptidos y no como amino‡cidos libres. Cuando el tama–o de los pŽptidos es de m‡s de tres amino‡cidos son hidrolizados por las enzimas del borde en cepillo intestinal, mientras que los pŽptidos peque–os, di pŽptidos y tri pŽptidos pueden ser absorbidos y alcanzar la circulaci—n sangu’nea sin alterar su estructura lo que les permite adem‡s de suministrar amino‡cidos, ejercer funciones en el tracto gastrointestinal o a nivel general. A estos pŽptidos con funciones biol—gicas se les denomina pŽptidos bioactivos y entre algunas de sus funciones est‡n la de modificar el metabolismo celular, actuar como vaso-reguladores, factores de crecimiento, inductores hormonales, inmunomoduladores o neurotransmisores.

Muchos de estos pŽptidos son inactivos dentro de la secuencia de la prote’na original y durante la digesti—n gastrointestinal o la hidr—lisis enzim‡tica, son liberados y adquieren sus propiedades.

Principales PŽptidos bioactivos presentes en el suero l‡cteo:


Los pŽptidos de suero pasan de forma r‡pida a travŽs del tracto gastrointestinal hasta llegar la zona del intestino donde van absorberse. Si el tama–o del pŽptido es el adecuado, pasa al torrente sangu’neo sin necesidad de ser hidrolizado a formas m‡s peque–as o amino‡cidos libres. De esta manera se consigue elevar m‡s r‡pidamente y en mayor medida los amino‡cidos plasm‡ticos que consumir otras formas de prote’nas o incluso que amino‡cidos en forma libre. Adicionalmente algunos pŽptidos presentes en el suero presentan beneficios adicionales sobre la salud como modulaci—n del sistema inmune o propiedades antiinflamatorias.

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